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Literature summary extracted from

  • Zakharov, V.; Lin, H.K.; Azzarello, J.; McMeekin, S.; Moore, K.N.; Penning, T.M.; Fung, K.M.
    Suppressed expression of type 2 3alpha/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) in endometrial hyperplasia and carcinoma (2010), Int. J. Clin. Exp. Pathol., 3, 608-617.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
1.1.1.64 medicine uniform, diffuse, and strong expression of isoform AKR1C3 in normal endometrial epithelium but not in endometrial stromal cells. The expression of AKR1C3 is reduced in both hyperplastic and carcinomatous endometrial epithelium Homo sapiens
1.1.1.213 medicine uniform, diffuse, and strong expression of isoform AKR1C3 in normal endometrial epithelium but not in endometrial stromal cells. The expression of AKR1C3 is reduced in both hyperplastic and carcinomatous endometrial epithelium Homo sapiens
1.1.1.239 medicine uniform, diffuse, and strong expression of isoform AKR1C3 in normal endometrial epithelium but not in endometrial stromal cells. The expression of AKR1C3 is reduced in both hyperplastic and carcinomatous endometrial epithelium Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.64 Homo sapiens P42330
-
-
1.1.1.213 Homo sapiens P42330
-
-
1.1.1.239 Homo sapiens P42330
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.64 endometrial cancer cell line uniform, diffuse, and strong expression of isoform AKR1C3 in normal endometrial epithelium but not in endometrial stromal cells. The expression of AKR1C3 is reduced in both hyperplastic and carcinomatous endometrial epithelium Homo sapiens
-
1.1.1.64 endometrial gland uniform, diffuse, and strong expression of isoform AKR1C3 in normal endometrial epithelium but not in endometrial stromal cells. The expression of AKR1C3 is reduced in both hyperplastic and carcinomatous endometrial epithelium Homo sapiens
-
1.1.1.213 endometrial cancer cell line uniform, diffuse, and strong expression of isoform AKR1C3 in normal endometrial epithelium but not in endometrial stromal cells. The expression of AKR1C3 is reduced in both hyperplastic and carcinomatous endometrial epithelium Homo sapiens
-
1.1.1.213 endometrial gland uniform, diffuse, and strong expression of isoform AKR1C3 in normal endometrial epithelium but not in endometrial stromal cells. The expression of AKR1C3 is reduced in both hyperplastic and carcinomatous endometrial epithelium Homo sapiens
-
1.1.1.239 endometrial cancer cell line uniform, diffuse, and strong expression of isoform AKR1C3 in normal endometrial epithelium but not in endometrial stromal cells. The expression of AKR1C3 is reduced in both hyperplastic and carcinomatous endometrial epithelium Homo sapiens
-
1.1.1.239 endometrial gland uniform, diffuse, and strong expression of isoform AKR1C3 in normal endometrial epithelium but not in endometrial stromal cells. The expression of AKR1C3 is reduced in both hyperplastic and carcinomatous endometrial epithelium Homo sapiens
-

Expression

EC Number Organism Comment Expression
1.1.1.64 Homo sapiens the expression of isoform AKR1C3 is reduced in both hyperplastic and carcinomatous endometrial epithelium down
1.1.1.213 Homo sapiens the expression of isoform AKR1C3 is reduced in both hyperplastic and carcinomatous endometrial epithelium down
1.1.1.239 Homo sapiens the expression of isoform AKR1C3 is reduced in both hyperplastic and carcinomatous endometrial epithelium down